Minimally invasive surgery in primary hyperparathyroidism

Abstract

Aim:  To describe the general and laboratory characteristics of patients with primary hyperparathyroidism (PHPT) who underwent surgery in our clinic, as well as surgery-related morbidity.

Methods: The study population were selected: Patients with clinical and radiological diagnosis of PHPT were included in the study. Minimal invasive parathyroid surgery, aimed only the affected gland, was chosen for the patients. Preoperative calcium (Ca), parathyroid hormone (PTH), and postoperative Ca and PTH levels were recorded. Preoperative sonography and scintigraphy studies to determine localization were obtained from the same database.

Results: 116 patients were undergone minimal invasive surgery for hyperparathyroidism, which is mainly focused on the pathological gland. The mean preoperative PHT was 397 ng/L and postoperative PTH was 53 ng/L. Preoperative and postoperative Ca levels were 11.7 mg/dL and 9.3 mg/dL, respectively. Histopathological evaluation revealed following results: 108 patients had adenoma. None of the subjects had malignancy. The mortality rate was 0% and the morbidity was 1.7%, related to this procedure.

Conclusion: According to the data in present study, we suggest that minimally invasive surgical techniques should be preferred in sake of higher success and lower postoperative morbidity in patients with a single gland disease.